Parth Bibekar

Parth Bibekar

PhD candidate at EPFL, Switzerland

I am a PhD candidate in Computational and Quantitative Biology at the Laboratory for Biomolecular Modeling, EPFL, advised by Prof. Matteo Dal Peraro. I work on machine learning for structural bioinformatics, computational biophysics and integrative modeling, and lately on designing RNA. Outside research I enjoy chess, close-up magic, traveling, reading, and building things.

Research

RISoTTo: context-aware RNA sequence design

A parameter-free geometric deep learning approach that generates RNA sequences conditioned on both their backbone scaffolds and the surrounding molecular context. Presented at the NeurIPS 2025 AI4D3 workshop.

Paper Code
RISoTTo method overview

PeSTo-Carbs: protein–carbohydrate interfaces

A geometric transformer extending PeSTo to predict binding interfaces between proteins and carbohydrates, including cyclodextrins. Featured on the cover of JCTC.

Paper Code Web server
PeSTo-Carbs method overview

Full list on the publications page.

Talks & Posters

  • Physics of Living Systems SeminarEPFL, SwitzerlandTalk
  • EPFL AIxBIO SeminarEPFL, SwitzerlandTalk
  • Swiss RNA WorkshopBern, SwitzerlandPoster
  • frontiers2026 Symposium on NanoBioEngineeringEPFL, SwitzerlandTalk
  • SIB AI4Biomolecules SIG SeminarBern, SwitzerlandTalk
  • NeurIPS AI4D3 WorkshopSan Diego, USAPoster
  • European RosettaConLjubljana, SloveniaPoster
  • Structure Based Drug DiscoverySestri Levante, ItalyPoster
  • European RosettaConCopenhagen, DenmarkPoster

Education

PhD, Computational and Quantitative Biology

EPFL, Switzerland

Advisor: Prof. Matteo Dal Peraro

BS-MS, Biology (minor in Computational and Data Sciences)

IISER Kolkata, India

Thesis: Applications of Geometric Deep Learning for Biomolecular Structure Modeling

Advisor: Prof. Matteo Dal Peraro

Teaching

EPFL iGEM Team

Supervised the computational and mathematical modeling of a synthetic biology project.

BIOENG-455 · Computational Cell Biology

Teaching assistant.

BIO-315 · Structural Biology

Teaching assistant for the molecular dynamics, molecular modeling, and cryo-EM modules.

EPFL campus overlooking Lake Geneva
The EPFL campus, overlooking Lac Léman

Let's connect

Always open to collaborating on interesting problems in RNA and protein design, computational biology, and structural bioinformatics.

parth.bibekar@epfl.ch
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